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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR2
All Species:
21.52
Human Site:
S411
Identified Species:
47.33
UniProt:
P21802
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P21802
NP_000132.3
821
92025
S411
T
K
K
P
D
F
S
S
Q
P
A
V
H
K
L
Chimpanzee
Pan troglodytes
XP_521622
819
91776
S411
T
K
K
P
D
F
S
S
Q
P
A
V
H
K
L
Rhesus Macaque
Macaca mulatta
XP_001106418
825
91775
V422
D
F
S
S
Q
P
A
V
H
K
L
T
K
R
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P21803
821
91965
S411
T
K
K
P
D
F
S
S
Q
P
A
V
H
K
L
Rat
Rattus norvegicus
Q04589
822
91806
S410
T
K
K
S
D
F
H
S
Q
M
A
V
H
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18461
823
92281
S413
T
K
K
P
D
F
S
S
Q
P
A
V
H
K
L
Frog
Xenopus laevis
Q03364
813
91322
R416
T
K
R
I
P
L
H
R
Q
V
T
V
S
A
D
Zebra Danio
Brachydanio rerio
Q8JG38
817
91370
S411
A
K
K
P
D
F
S
S
Q
P
A
V
H
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09147
1052
117795
K635
L
R
R
E
K
L
L
K
L
R
I
E
T
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
H554
M
V
C
K
Q
T
L
H
K
K
G
F
M
D
D
Sea Urchin
Strong. purpuratus
Q26614
972
110463
C570
V
T
C
I
A
I
L
C
K
Q
T
Q
V
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.3
N.A.
N.A.
96.9
71.7
N.A.
N.A.
92.8
77.5
77.4
N.A.
29
N.A.
31.6
34.4
Protein Similarity:
100
99.6
90.9
N.A.
N.A.
98.1
83.8
N.A.
N.A.
96.3
87.2
86.5
N.A.
45.1
N.A.
46.5
51.7
P-Site Identity:
100
100
0
N.A.
N.A.
100
80
N.A.
N.A.
100
26.6
93.3
N.A.
0
N.A.
0
0
P-Site Similarity:
100
100
20
N.A.
N.A.
100
80
N.A.
N.A.
100
33.3
93.3
N.A.
13.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
0
0
0
55
0
0
10
0
% A
% Cys:
0
0
19
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
55
0
0
0
0
0
0
0
0
10
19
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
55
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
19
10
10
0
0
0
55
0
19
% H
% Ile:
0
0
0
19
0
10
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
64
55
10
10
0
0
10
19
19
0
0
10
55
0
% K
% Leu:
10
0
0
0
0
19
28
0
10
0
10
0
0
0
55
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
46
10
10
0
0
0
46
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
0
0
64
10
0
10
0
0
0
% Q
% Arg:
0
10
19
0
0
0
0
10
0
10
0
0
0
19
0
% R
% Ser:
0
0
10
19
0
0
46
55
0
0
0
0
10
0
0
% S
% Thr:
55
10
0
0
0
10
0
0
0
0
19
10
10
0
0
% T
% Val:
10
10
0
0
0
0
0
10
0
10
0
64
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _